Health Benefits of Wine


Project Number
UCT 01 2002

Project title
Health benefits of wine

Project leader
Blackhurst, D M

Institution
University of Cape Town. Faculty of Health Sciences.

Team members
Blackhurst, D M

Project description
Project 2001 is basically a continuation of work done in the past few years, testing the antioxidant capability of wine in lipid peroxidation systems. In other words does wine have health benefits in this field? Work wise the project may be broadly divided into two stages: completion of work begun in 2000 where the ability of wine to reduce lipid peroxidation of unsaturated fatty acids in meat (red meat, chicken and fish) was checked during cooking. A full report with details of all the results was submitted to Winetech in October 2001. An interesting and potentially very promising result was seen after marinating red meat in red wine. Six similar experiments showed that marinating with red wine decreased the concentration of all lipid peroxidation products tested in red meat after microwave cooking. (This form of cooking was used because it is easy and reproducible). A statistical trend was revealed on student analysis and we are optimistic that a larger number of samples should bring the p-value to statistical significance.

The second stage of Project 2001 involved human volunteers and testing the lipid peroxidation status of their chylomicrons after ingestion of polyunsaturated fatty acids in the form of a milkshake containing sunflower oil with and without wine. Details are available in the full report of October 2001. To date seven volunteers have been tested. Analysis of the kinetics of copper-induced oxidation of the chylomicrons show more similarities than differences between the two sets of chylomicrons. The biggest area of difference appears to be in the phase of decline. However as it was originally intended that approximately twelve volunteers be tested, a few more experiments need to be done before finally analysing these data.

Presentation(s)
Blackhurst, D M and Marais, A D. 2000. Lipid oxidation in edible oils: An evaluation using three spectrophotometric methods. Paper presented at the 6th LASSA Congress. Cape Town, South Africa.

Blackhurst, D M and Marais, A D. 2000. Lipid peroxidation status of edible oils in South Africa. Paper presented at the 18th Congress of the Nutrition Society of South Africa. Durban, South Africa.

Blackhurst, D M and Marais, A D. 2000. The antioxidant effects of wine on lipid oxidation in edible oils. Presentation at the 27th Research Day, University of Cape Town. Faculty of Health Sciences. Cape Town, South Africa.

Blackhurst, D M and Marais, A D. 2002. Concomitant consumption of wine and edible oil does not influence the peroxidation status of chylomicrons. Paper presented at the 7th LASSA Congress. Cape Town, South Africa.

Blackhurst, D M and Marais, A D. 2002. Marinating beef with red wine may protect against lipid peroxidation during cooking. Presentation at the 29th Research Day. University of Cape Town. Faculty of Health Sciences. Cape Town, South Africa.

Blackhurst, D M and Marais, A D. 2002. Concomitant consumption of wine and edible oil does not influence the peroxidation status of chylomicrons. Paper presented at the International Congress on Wine and Health. 20-23 October, Chile.

Blackhurst, D M and Marais, A D. 2002. Marinating beef with red wine may protect against lipid peroxidation during cooking. Paper presented at the International Congress on Wine and Health. 20-23 October, Chile.
Paper presented at the International of Wine and Health. 20-23 October, Chile.

Blackhurst, D M, Van Velden, D P, Mansvelt, E P G, Marais, A D, Wolmarans, P, Fourie, E and Levey, M J. 2002. The lipid peroxidation status of LDL after a Mediterranean-like diet with and without red wine. Paper presented at the International Congress on Wine and Health. 20-23 October, Chile.

Blackhurst, D M, Wolmarans, K H, Freislich, J E and Marais, A D. 2003. Wine dilates the brachial artery but does not increase flow mediated dilatation. Presentation at the 30th Research Day. University of Cape Town. Faculty of Health Sciences. October, Cape Town, South Africa.

Blackhurst, D M, Wolmarans, K H, Freislich, J E and Marais, A D. 2004. Wine dilates the brachial artery but does not increase flow mediated dilatation over two hours. Paper presented at the 8th LASSA Congress. Durban. South Africa.

Blackhurst, D M and Marais, A D. 2004. Red wine consumption increases plasma catechin concentration but not plasma ORAC. Paper presented at the 8th LASSA Congress. Durban, South Africa.

Van Velden, D P, Wolmarans, P, Fourie, E, Nel, D, Marais, A D and Blackhurst, D M. 2004. The influence of a Mediterranean-like diet with and without red wine on the criteria related to the metabolic syndrome. Paper presented at the 28th World Congress of Vine and Wine and the 84th General Assembly of the OIV. 4-9 July 2004, Vienna, Austria.

Blackhurst, D M, Wolmarans, K H and Marais, A D. 2005. Wine dilates the brachial artery, but does not increase flow mediated dilatation over 2 hours. Paper presented at the International Congress on Health and Wine: Vindaba 2005. 13-16 September, Stellenbosch, South Africa.

Blackhurst, D M and Marias, A D. 2005. Concomitant consumption of red wine and edible oil does not influence the peroxidation status of chylomicron lipids despite increasing plasma catechin concentration. Paper presented at the 26th World Congress and Exhibition of the International Society for Fat Research. 25-28 September, Prague, Czech Republic.

Blackhurst, D M. 2006. Wine limits peroxidation of edible lipids. Paper presented at the Antioxidant Symposium. August, Stellenbosch, South Africa.

Van Velden, D P, Van der Merwe, S, Fourie, E, Kidd, M, Blackhurst, D M, Kotze, M J and Mansvelt, E P G. 2006. The influence of a Mediterranean-like diet with and without red wine on patients with the metabolic syndrome. Paper presented at the Nutrition Congress. 24-27 September, Port Elizabeth, South Africa.

Blackhurst, D M and Marais, A D. 2007. Acute consumption of red wine neither affects plasma ORAC value nor significantly protects human erythrocytes against radical-induced haemolysis. Paper presented at the 3rd International Wine and Health Congress. 20-22 September, Bordeaux, France.

Article
Blackhurst, D M, Marais, A D. 2000. Lipid peroxidation status of edible oils in South Africa, South African Journal of Clinical Nutrition, v. 13 (3)

Marais, A D, Blackhurst, D M. 2001. Wine, acting as an antioxidant may have health benefits, WineLand, Mnth Jul (p. 115 – 116)

Marais, A D, Blackhurst, D M. 2001. Die uitwerking van alkohol verbruik op gesondheid: Oorsig, WineLand, Mnth Jul (p. 65-66)

Blackhurst, D M, Marais, A D. 2003. Marinating red meat in red wine may have health benefits, WineLand, Mnth Sep (p. 98)

Blackhurst, D M, Marais, A D. 2005. Alcohol – foe or friend? South African Medical Journal, v. 95 (9) (p. 648-656)

Blackhurst, D M, Marais, A D. 2006. Concomitant consumption of red wine and polyunsaturated fatty acids in edible oil does not influence the peroxidation status of chylomicron lipids despite increasing plasm catechin, Nutrition, Metabolism and Cardiovascular Diseases, v. 16 (p. 550-558)

Blackhurst, D M, Marais, A D. 2006. Health effects of alcohol consumption: review, Wynboer Technical Yearbook, (p. 17-18)

Lecour, S, Blackhurst, D M, Marais, A D, Opie, L H. 2006. Lowering the degree of alcohol in red wine does not alter its cardiovascular effect, Journal of Molecular and Cellular Cardiology, Mnth June v. 40 (6) (p. 997-998)

Van Velden, D P, Van der Merwe, S, Fourie, E, Kidd, M, Blackhurst, D M, Kotze, M J, Mansvelt, E P G. 2006. The influence of a Mediterranean-like diet with and without red wine on patients with metabolic syndrome, South African Journal of Clinical Nutrition, Mnth Sep v. 19 (3) (p. S1-S28)

Blackhurst, D M, Wolmarans, K H, Marais, A D. 2007. Wine dilates the brachial artery but does not increase flow-mediated dilation over two hours, South African Journal of Enology and Viticulture, v. 28 (1) (p. 11-16)
Article.pdf

Mansvelt, E P G, Fourie, E, Blackhurst, D M, Stofberg, H, Van der Merwe, S, Kotze, M J, Van Velden, D P. 2007. The influence of a Mediterranean diet with and without red wine on the haemostatic and inflammatory parameters of subjects with the metabolic syndrome, South African Journal of Enology and Viticulture, v. 28 (1) (p. 37-43)
Article.pdf

Van Velden, D P, Van der Merwe, S, Fourie, E, Kidd, M, Blackhurst, D M, Kotze, M J, Mansvelt, E P G. 2007. The short term influence of a Mediterranean type diet and mild exercise with and without red wine on patients with the metabolic syndrome, South African Journal of Enology and Viticulture, v. 28 (1) (p. 44-49)
Article.pdf

Blackhurst, D M, Wolmarans, K H, Marais, A D. 2009. Do heavy metals counter the potential health benefits of wine? Journal of Endocrinology, Metabolism and Diabetes of South Africa, v. 14 (2) (p. 77-79)

Blackhurst, D M, Marais, A D. 2009. Die impak van swaar metale in wyn op gesondheid, WineLand, Mnth Nov (p. 107-108)

Blackhurst, D M, Marais, A D. 2009. Gesondheidsvoordele van wyne met minder alkohol, WineLand, Mnth Dec (p. 63-64)

FinalReport.pdf

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